WNK3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human WNK3 partial ORF ( NP_065973, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATDSGDPASTEDSEKPDGISFENRVPQVAATLTVEARLKEKNSTFSASGETVERKRFFRKSVEMTEDDKVAESSPKDERIKAAMNIPRVDKLPSNVLRG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (81); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — WNK3
Entrez GeneID
65267GeneBank Accession#
NM_020922Protein Accession#
NP_065973Gene Name
WNK3
Gene Alias
KIAA1566, PRKWNK3
Gene Description
WNK lysine deficient protein kinase 3
Omim ID
300358Gene Ontology
HyperlinkGene Summary
Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM
Other Designations
OTTHUMP00000023369|protein kinase, lysine deficient 3
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Interactome
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Disease
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