NOL6 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NOL6 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NOL6 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NOL6 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NOL6
Entrez GeneID
65083GeneBank Accession#
NOL6Gene Name
NOL6
Gene Alias
FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
Gene Description
nucleolar protein family 6 (RNA-associated)
Omim ID
611532Gene Ontology
HyperlinkGene Summary
The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000000449|OTTHUMP00000000450|OTTHUMP00000000451|OTTHUMP00000000452|nucleolar protein family 6
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Interactome
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