ACD 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ACD full-length
Host
Human
Theoretical MW (kDa)
59.95
Interspecies Antigen Sequence
Mouse (59); Rat (61)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ACD antibody (H00065057-B01) by Western Blots.
SDS-PAGE Gel
ACD transfected lysate.
Western Blot
Lane 1: ACD transfected lysate ( 59.95 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ACD
Entrez GeneID
65057GeneBank Accession#
BC016904.1Protein Accession#
-Gene Name
ACD
Gene Alias
PIP1, PTOP, TINT1, TPP1
Gene Description
adrenocortical dysplasia homolog (mouse)
Omim ID
609377Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq
Other Designations
POT1 and TIN2 organizing protein|TIN2 interacting protein 1|adrenocortical dysplasia homolog
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Interactome
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Disease
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