PINK1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PINK1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PINK1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PINK1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PINK1
Entrez GeneID
65018GeneBank Accession#
PINK1Gene Name
PINK1
Gene Alias
BRPK, FLJ27236, PARK6
Gene Description
PTEN induced putative kinase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq
Other Designations
OTTHUMP00000002881|protein kinase BRPK|serine/threonine-protein kinase PINK1
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Interactome
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Disease
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