DCLRE1B rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DCLRE1B peptide using ARM Technology.
Immunogen
A synthetic peptide of human DCLRE1B is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DCLRE1B peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DCLRE1B
Entrez GeneID
64858GeneBank Accession#
DCLRE1BGene Name
DCLRE1B
Gene Alias
APOLLO, DKFZp686C24187, FLJ12810, FLJ13998, SNM1B
Gene Description
DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
Omim ID
609683Gene Ontology
HyperlinkGene Summary
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM
Other Designations
OTTHUMP00000013722
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Interactome
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