CYP3A43 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CYP3A43 protein.
Immunogen
CYP3A43 (AAI00983.1, 1 a.a. ~ 280 a.a) full-length human protein.
Sequence
MNLETGNGPHHFPMWRYVGEKPEAGSREQQVHQLERFLWGLHHGCNHWHIIWSELGFSQQSTRSLSEKYEEAFKIGFFGSLFTLNIQSLAVLPRPECMVRSGLTETSTSWVRVILLPQPPEELGLQHRVDFFQQIIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERSH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CYP3A43 MaxPab polyclonal antibody. Western Blot analysis of CYP3A43 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of CYP3A43 expression in transfected 293T cell line (H00064816-T01) by CYP3A43 MaxPab polyclonal antibody.
Lane 1: CYP3A43 transfected lysate(30.8 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CYP3A43
Entrez GeneID
64816GeneBank Accession#
BC100982.2Protein Accession#
AAI00983.1Gene Name
CYP3A43
Gene Alias
MGC119315, MGC119316
Gene Description
cytochrome P450, family 3, subfamily A, polypeptide 43
Omim ID
606534Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
cytochrome P450 polypeptide 43|cytochrome P450, subfamily IIIA, polypeptide 43
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