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P2RY12 rabbit monoclonal antibody

  • Catalog # : H00064805-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human P2RY12 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human P2RY12 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human P2RY12 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Gene Name:
  • P2RY12
  • Gene Alias:
  • ADPG-R,HORK3,P2T(AC),P2Y(AC),P2Y(ADP),P2Y(cyc),P2Y12,SP1999
  • Gene Description:
  • purinergic receptor P2Y, G-protein coupled, 12
  • Gene Summary:
  • The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • ADP-glucose receptor,G-protein coupled receptor SP1999,Gi-coupled ADP receptor HORK3,P2Y purinoceptor 12,platelet ADP receptor,purinergic receptor P2RY12,purinergic receptor P2Y12,putative G-protein coupled receptor
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