ACBD3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Tissue lysate)
ACBD3 MaxPab polyclonal antibody. Western Blot analysis of ACBD3 expression in human pancreas.
Western Blot (Cell lysate)
ACBD3 MaxPab polyclonal antibody. Western Blot analysis of ACBD3 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of ACBD3 expression in transfected 293T cell line (H00064746-T01) by ACBD3 MaxPab polyclonal antibody.
Lane1:ACBD3 transfected lysate(58.08 KDa).
Lane2:Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ACBD3 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ACBD3 protein.
Immunogen
ACBD3 (AAH60792.1, 1 a.a. ~ 528 a.a) full-length human protein.
Sequence
MAAVLNAERLEVSVDGLTLSPDPEERPGAEGAPLLPPPLPPPSPPGSGRGPGASGEQPEPGEAAAGGAAEEARRLEQRWGFGLEELYGLALRFFKEKDGKAFHPTYEEKLKLVALHKQVLMGPYNPDTCPEVGFFDVLGNDRRREWAALGNMSKEDAMVEFVKLLNRCCHLFSTYVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQLYQVQLAQQQAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPEAAEEALENGPKESLPVIAAPSMWTRPQIKDFKEKIQQDADSVITVGRGEVVTVRVPTHEEGSYLFWEFATDNYDIGFGVYFEWTDSPNTAVSVHVSESSDDDEEEEENIGCEEKAKKNANRPLLDEIVPVYRRDCHEEVYAGSHQYPGRGVYLLKFDNSYSLWRSKSVYYRVYYTR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ACBD3 MaxPab polyclonal antibody. Western Blot analysis of ACBD3 expression in human pancreas.Western Blot (Cell lysate)
ACBD3 MaxPab polyclonal antibody. Western Blot analysis of ACBD3 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of ACBD3 expression in transfected 293T cell line (H00064746-T01) by ACBD3 MaxPab polyclonal antibody.
Lane1:ACBD3 transfected lysate(58.08 KDa).
Lane2:Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to ACBD3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — ACBD3
Entrez GeneID
64746GeneBank Accession#
BC060792.1Protein Accession#
AAH60792.1Gene Name
ACBD3
Gene Alias
GCP60, GOCAP1, GOLPH1, PAP7
Gene Description
acyl-Coenzyme A binding domain containing 3
Omim ID
606809Gene Ontology
HyperlinkGene Summary
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq
Other Designations
OTTHUMP00000035668|PBR associated protein|PKA (RIalpha)-associated protein|golgi complex associated protein 1, 60kDa|golgi phosphoprotein 1|golgi resident protein GCP60|peripherial benzodiazepine receptor associated protein
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Interactome
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Disease
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Publication Reference
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An A-Kinase Anchoring Protein (ACBD3) Coordinates Traffic-Induced PKA Activation At The Golgi.
Jie Jia, Shuocheng Tang, Xihua Yue, Shuaiyang Jing , Lianhui Zhu, Chuanting Tan, Jingkai Gao, Yulei Du, Intaek Lee, Yi Qian.
The Journal of Biological Chemistry 2023 May; 299(5):104696.
Application：IF, WB-Tr, Human, HeLa, U2OS cells.
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ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.
Xihua Yue, Yi Qian, Lianhui Zhu, Bopil Gim, Mengjing Bao, Jie Jia, Shuaiyang Jing, Yijing Wang, Chuanting Tan, Francesca Bottanelli, Pascal Ziltener, Sunkyu Choi, Piliang Hao, Intaek Lee.
BMC Biology 2021 Sep; 19(1):194.
Application：IF, WB-Tr, Human, HeLa cells.
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An A-Kinase Anchoring Protein (ACBD3) Coordinates Traffic-Induced PKA Activation At The Golgi.
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