TMPRSS3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TMPRSS3 partial ORF (NP_076927.1, 119 a.a. - 214 a.a.) recombinant protein with GST tag at N-terminal.
Sequence
VFTAASWKTMCSDDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVREGCASGHVVTLQCTACGHRRGYS
Theoretical MW (kDa)
36.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TMPRSS3
Entrez GeneID
64699GeneBank Accession#
NM_024022.2Protein Accession#
NP_076927.1Gene Name
TMPRSS3
Gene Alias
DFNB10, DFNB8, ECHOS1, TADG12
Gene Description
transmembrane protease, serine 3
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
OTTHUMP00000109345|serine protease TADG12
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Interactome
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Disease
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