ANAPC1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ANAPC1 partial ORF ( NP_073153, 1841 a.a. - 1944 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLRLAPLLLGNPQPMVM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.18
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ANAPC1
Entrez GeneID
64682GeneBank Accession#
NM_022662Protein Accession#
NP_073153Gene Name
ANAPC1
Gene Alias
APC1, MCPR, TSG24
Gene Description
anaphase promoting complex subunit 1
Omim ID
608473Gene Ontology
HyperlinkGene Summary
ANAPC1 is 1 of at least 10 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.[supplied by OMIM
Other Designations
anaphase-promoting complex 1 (meiotic checkpoint regulator)
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Interactome
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Pathway
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