CLEC7A 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
CLEC7A transfected lysate
Western Blot
Lane 1: CLEC7A transfected lysate ( 8.4 KDa).
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CLEC7A full-length
Host
Human
Theoretical MW (kDa)
8.4
Interspecies Antigen Sequence
Mouse (60); Rat (57)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CLEC7A antibody (H00064581-B02) by Western Blots.
SDS-PAGE Gel
CLEC7A transfected lysate
Western Blot
Lane 1: CLEC7A transfected lysate ( 8.4 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CLEC7A
Entrez GeneID
64581GeneBank Accession#
NM_197954Protein Accession#
NP_922945Gene Name
CLEC7A
Gene Alias
BGR, CLECSF12, DECTIN1
Gene Description
C-type lectin domain family 7, member A
Omim ID
606264Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq
Other Designations
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12|beta-glucan receptor|dectin-1|dendritic cell-associated C-type lectin 1|dendritic cell-associated C-type lectin-1|lectin-like receptor 1
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Interactome
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Disease
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