CLEC7A MaxPab mouse polyclonal antibody (B03P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CLEC7A expression in transfected 293T cell line (H00064581-T05) by CLEC7A MaxPab polyclonal antibody.
Lane 1: CLEC7A transfected lysate(8.58 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CLEC7A protein.
Immunogen
CLEC7A (AAH13385, 1 a.a. ~ 77 a.a) full-length human protein.
Sequence
MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGTMAGFKAVEFKG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (57)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CLEC7A expression in transfected 293T cell line (H00064581-T05) by CLEC7A MaxPab polyclonal antibody.
Lane 1: CLEC7A transfected lysate(8.58 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CLEC7A
Entrez GeneID
64581GeneBank Accession#
BC013385Protein Accession#
AAH13385Gene Name
CLEC7A
Gene Alias
BGR, CLECSF12, DECTIN1
Gene Description
C-type lectin domain family 7, member A
Omim ID
606264Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq
Other Designations
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12|beta-glucan receptor|dectin-1|dendritic cell-associated C-type lectin 1|dendritic cell-associated C-type lectin-1|lectin-like receptor 1
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Interactome
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Disease
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