ALDH8A1 mouse monoclonal antibody (hybridoma)
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ALDH8A1.
Immunogen
ALDH8A1 (NP_072090.1, 1 a.a. ~ 487 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAGTNALLMLENFIDGKFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQSLEEFAQAESKDQGKTLALARTMDIPRSVQNFRFFASSSLHHTSECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAPHCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITVKH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89)
Quality Control Testing
Antibody reactivity and specificity confirmed by ELISA and Western Blot.
Deliverables
Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
Note
Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
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Applications
Western Blot (Transfected lysate)
Western Blot (Recombinant protein)
ELISA
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Gene Info — ALDH8A1
Entrez GeneID
64577GeneBank Accession#
NM_022568.2Protein Accession#
NP_072090.1Gene Name
ALDH8A1
Gene Alias
ALDH12, DJ352A20.2, DKFZp779D2315, MGC138650
Gene Description
aldehyde dehydrogenase 8 family, member A1
Omim ID
606467Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
aldehyde dehydogenase 8 family, member A1|aldehyde dehydrogenase 12|aldehyde dehydrogenase 8A1|aldehyde dehydrogenase family protein
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Interactome
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