CPEB1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CPEB1 full-length ORF ( NP_001073002.1, 1 a.a. - 486 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLFPTSAQESSRGLPDANDLCLGLQSLSLTGWDRPWSTQDSDSSAQSSTHSVLSMLHNPLGNVLGKPPLSFLPLDPLGSDLVDKFPAPSVRGSRLDTRPILDSRSSSPSDSDTSGFSSGSDHLSDLISSLRISPPLPFLSLSGGGPRDPLKMGVGSRMDQEQAALAAVTPSPTSASKRWPGASVWPSWDLLEAPKDPFSIEREARLHRQAAAVNEATCTWSGQLPPRNYKNPIYSCKVFLGGVPWDITEAGLVNTFRVFGSLSVEWPGKDGKHPRCPPKGYVYLVFELEKSVRSLLQACSHDPLSPDGLSEYYFKMSSRRMRCKEVQVIPWVLADSNFVRSPSQRLDPSRTVFVGALHGMLNAEALAAILNDLFGGVVYAGIDTDKHKYPIGSGRVTFNNQRSYLKAVSAAFVEIKTTKFTKKVQIDPYLEDSLCHICSSQPGPFFCRDQVCFKYFCRSCWHWRHSMEGLRHHSPLMRNQKNRDSS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
80
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CPEB1
Entrez GeneID
64506GeneBank Accession#
NM_001079534.1Protein Accession#
NP_001073002.1Gene Name
CPEB1
Gene Alias
CEBP, CPE-BP1, CPEB, FLJ13203, MGC34136, MGC60106
Gene Description
cytoplasmic polyadenylation element binding protein 1
Omim ID
607342Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CPE-binding protein 1
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Interactome
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Pathway
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Disease
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Publication Reference
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CPEB1 Regulates the Expression of MTDH/AEG-1 and Glioblastoma Cell Migration.
Kochanek DM, Wells DG.
Molecular Cancer Research 2013 Feb; 11(2):149.
Application：WB, Mouse, Astrocytes.
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CPEB1 Regulates the Expression of MTDH/AEG-1 and Glioblastoma Cell Migration.
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