DCLRE1C (Human) Recombinant Protein (P01)
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Specification
Product Description
Human DCLRE1C full-length ORF ( AAH22254, 1 a.a. - 434 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILRHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCRSSQSTEPKYKPLGKLKRARTVHRDSGSHSVTQARMRWCHHDSLYPLTPGIKRSSCLSLLTSWITGAYRHAQLMI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
73.48
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DCLRE1C
Entrez GeneID
64421GeneBank Accession#
BC022254Protein Accession#
AAH22254Gene Name
DCLRE1C
Gene Alias
A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C
Gene Description
DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq
Other Designations
OTTHUMP00000019166|OTTHUMP00000019167|OTTHUMP00000019168|OTTHUMP00000019170|OTTHUMP00000019171|OTTHUMP00000019172|OTTHUMP00000019174|OTTHUMP00000045150|artemis protein|severe combined immunodeficiency, type a (Athabascan)
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Interactome
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Pathway
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Disease
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