FTS 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FTS full-length
Host
Human
Theoretical MW (kDa)
33.1
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FTS antibody (H00064400-B01) by Western Blots.
SDS-PAGE Gel
FTS transfected lysate
Western Blot
Lane 1: FTS transfected lysate ( 33.1 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — AKTIP
Entrez GeneID
64400GeneBank Accession#
NM_022476Protein Accession#
NP_071921Gene Name
AKTIP
Gene Alias
FT1, FTS
Gene Description
AKT interacting protein
Omim ID
608483Gene Ontology
HyperlinkGene Summary
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq
Other Designations
fused toes homolog
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Interactome
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Disease
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