AKTIP purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of AKTIP expression in transfected 293T cell line (H00064400-T01) by AKTIP MaxPab polyclonal antibody.
Lane 1: FTS transfected lysate(32.12 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human AKTIP protein.
Immunogen
AKTIP (NP_071921.1, 1 a.a. ~ 292 a.a) full-length human protein.
Sequence
MNPFWSMSTSSVRKRSEGEEKTLTGDVKTSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLVFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTASPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKPEEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of AKTIP expression in transfected 293T cell line (H00064400-T01) by AKTIP MaxPab polyclonal antibody.
Lane 1: FTS transfected lysate(32.12 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — AKTIP
Entrez GeneID
64400GeneBank Accession#
NM_022476Protein Accession#
NP_071921.1Gene Name
AKTIP
Gene Alias
FT1, FTS
Gene Description
AKT interacting protein
Omim ID
608483Gene Ontology
HyperlinkGene Summary
The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq
Other Designations
fused toes homolog
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Interactome
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Disease
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