MPP5 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MPP5.
Immunogen
MPP5 (NP_071919, 79 a.a. ~ 177 a.a) partial recombinant protein with GST tag.
Sequence
LDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKAS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MPP5
Entrez GeneID
64398GeneBank Accession#
NM_022474Protein Accession#
NP_071919Gene Name
MPP5
Gene Alias
FLJ12615, PALS1
Gene Description
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
Omim ID
606958Gene Ontology
HyperlinkGene Summary
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM
Other Designations
MAGUK p55 subfamily member 5|membrane protein, palmitoylated 5|stardust
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Interactome
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Pathway
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Publication Reference
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The multi-PDZ domain protein-1 (MUPP-1) expression regulates cellular levels of the PALS-1/PATJ polarity complex.
Assemat E, Crost E, Ponserre M, Wijnholds J, Le Bivic A, Massey-Harroche D.
Experimental Cell Research 2013 Oct; 319(17):2513.
Application:IP, WB-Ce, WB-Tr, Human, MCF-7, MCF-10A cells.
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The multi-PDZ domain protein-1 (MUPP-1) expression regulates cellular levels of the PALS-1/PATJ polarity complex.
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