ZMAT3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ZMAT3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ZMAT3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ZMAT3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ZMAT3
Entrez GeneID
64393GeneBank Accession#
ZMAT3Gene Name
ZMAT3
Gene Alias
FLJ12296, MGC10613, PAG608, WIG-1, WIG1
Gene Description
zinc finger, matrin type 3
Omim ID
606452Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq
Other Designations
WIG-1/PAG608 protein|p53 target zinc finger protein|zinc finger protein WIG1
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Interactome
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Pathway
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