GREM2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
GREM2 transfected lysate.
Western Blot
Lane 1: GREM2 transfected lysate ( 19.4 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-GREM2 full-length
Host
Human
Theoretical MW (kDa)
19.4
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GREM2 antibody (H00064388-B01) by Western Blots.
SDS-PAGE Gel
GREM2 transfected lysate.
Western Blot
Lane 1: GREM2 transfected lysate ( 19.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GREM2
Entrez GeneID
64388GeneBank Accession#
BC046632.1Protein Accession#
-Gene Name
GREM2
Gene Alias
CKTSF1B2, DAND3, PRDC
Gene Description
gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
Omim ID
608832Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq
Other Designations
OTTHUMP00000037834|cysteine knot superfamily 1, BMP antagonist 2|gremlin 2|protein related to DAN and cerberus
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