HIF3A 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HIF3A full-length
Host
Human
Theoretical MW (kDa)
73.7
Interspecies Antigen Sequence
Mouse (82); Rat (80)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HIF3A antibody (H00064344-B02) by Western Blots.
SDS-PAGE Gel
HIF3A transfected lysate.
Western Blot
Lane 1: HIF3A transfected lysate ( 73.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HIF3A
Entrez GeneID
64344GeneBank Accession#
BC080551.1Protein Accession#
AAH80551.1Gene Name
HIF3A
Gene Alias
HIF-3A, HIF-3A2, HIF-3A4, IPAS, MOP7, PASD7, bHLHe17
Gene Description
hypoxia inducible factor 3, alpha subunit
Omim ID
609976Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hypoxia-inducible factor-3 alpha 4|inhibitory PAS domain protein
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