HIF3A (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human HIF3A full-length ORF ( AAH26308.1, 1 a.a. - 363 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MALGLQRARSTTELRKEKSRDAARSRRSQETEVLYQLAHTLPFARGVSAHLDKASIMRLTISYLRMHRLCAAGEWNQVGAGGEPLDACYLKALEGFVMVLTAEGDMAYLSENVSKHLGLSQLELIGHSIFDFIHPCDQEELQDALTPQQTLSRRKVEARTERCFSLRMKSTLTSRGRTLNLKAATWKVLNCSGHMRAYKPPAQTSPAGSPDSEPPLQCLVLICEAIPHPGSLEPPLGRGAFLSRHSLDMKFTYCDDRIAEVAGYSPDDLIGCSAYEYIHALDSDAVSKSIHTCMYPISPGAKPAATWPPADTRTPQLPIPQDALPPHLNTSSLLPKPQGTVSFLAPSYPVPRSFSPHLPPWWP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
65.67
Interspecies Antigen Sequence
Mouse (82); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HIF3A
Entrez GeneID
64344GeneBank Accession#
BC026308Protein Accession#
AAH26308.1Gene Name
HIF3A
Gene Alias
HIF-3A, HIF-3A2, HIF-3A4, IPAS, MOP7, PASD7, bHLHe17
Gene Description
hypoxia inducible factor 3, alpha subunit
Omim ID
609976Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hypoxia-inducible factor-3 alpha 4|inhibitory PAS domain protein
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