HIF3A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HIF3A peptide using ARM Technology.
Immunogen
A synthetic peptide of human HIF3A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HIF3A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HIF3A
Entrez GeneID
64344GeneBank Accession#
HIF3AGene Name
HIF3A
Gene Alias
HIF-3A, HIF-3A2, HIF-3A4, IPAS, MOP7, PASD7, bHLHe17
Gene Description
hypoxia inducible factor 3, alpha subunit
Omim ID
609976Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hypoxia-inducible factor-3 alpha 4|inhibitory PAS domain protein
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