LMBR1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human LMBR1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — LMBR1
Entrez GeneID
64327GeneBank Accession#
NM_022458.2Protein Accession#
NP_071903.2Gene Name
LMBR1
Gene Alias
ACHP, C7orf2, DIF14, FLJ11665, PPD2, TPT
Gene Description
limb region 1 homolog (mouse)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq
Other Designations
differentiation-related gene 14|limb region 1 protein
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Interactome
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Disease
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