STRA6 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Western Blot (Tissue lysate)
STRA6 MaxPab rabbit polyclonal antibody. Western Blot analysis of STRA6 expression in mouse stomach.
Western Blot (Transfected lysate)
Western Blot analysis of STRA6 expression in transfected 293T cell line (H00064220-T02) by STRA6 MaxPab polyclonal antibody.
Lane 1: STRA6 transfected lysate(73.50 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human STRA6 protein.
Immunogen
STRA6 (AAH25256.1, 1 a.a. ~ 667 a.a) full-length human protein.
Sequence
MSSQPAGNQTSPGATEDYSYGSWYIDEPQGGEELQPEGEVPSCHTSIPPGLYHACLASLSILVLLLLAMLVRRRQLWPDCVRGRPGLPSPVDFLAGDRPRAVPAAVFMVLLSSLCLLLPDEDALPFLTLASAPSQDGKTEAPRGAWKILGLFYYAALYYPLAACATAGHTAAHLLGSTLSWAHLGVQVWQRAECPQVPKIYKYYSLLASLPLLLGLGFLSLWYPVQLVRSFSRRTGAGSKGLQSSYSEEYLRNLLCRKKLGSSYHTSKHGFLSWARVCLRHCIYTPQPGFHLPLKLVLSATLTGTAIYQVALLLLVGVVPTIQKVRAGVTTDVSYLLASFGIVLSEDKQEVVELVKHHLWALEVCYISALVLSCLLTFLVLMRSLVTHRTNLRALHRGAALDLSPLHRSPHPSRQAIFCWMSFSAYQTAFICLGLLVQQIIFFLGTTALAFLVLMPVLHGRNLLLFRSLESSWPFWLTLALAVILQNMAAHWVFLETHDGHPQLTNRRVLYAATFLLFPLNVLVGAMVATWRVLLSALYNAIHLGQMDLSLLPPRAATLDPGYYTYRNFLKIEVSQSHPAMTAFCSLLLQAQSLLPRTMAAPQDSLRPGEEDEGMQLLQTKDSMAKGARPGASRGRARWGLAYTLLHNPTLQVFRKTALLGANGAQP
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (73); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
STRA6 MaxPab rabbit polyclonal antibody. Western Blot analysis of STRA6 expression in mouse stomach.Western Blot (Transfected lysate)
Western Blot analysis of STRA6 expression in transfected 293T cell line (H00064220-T02) by STRA6 MaxPab polyclonal antibody.
Lane 1: STRA6 transfected lysate(73.50 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — STRA6
Entrez GeneID
64220GeneBank Accession#
BC025256Protein Accession#
AAH25256.1Gene Name
STRA6
Gene Alias
FLJ12541, MCOPS9, PP14296
Gene Description
stimulated by retinoic acid gene 6 homolog (mouse)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane protein involved in the metabolism of retinol. The encoded protein acts as a receptor for retinol/retinol binding protein complexes. This protein removes the retinol from the complex and transports it across the cell membrane. Defects in this gene are a cause of syndromic microphthalmia type 9 (MCOPS9). Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000176858|stimulated by retinoic acid gene 6 homolog
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Interactome
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Disease
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Publication Reference
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Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A.
Jean Moon, Srinivasagan Ramkumar, Johannes von Lintig.
Journal of Lipid Research 2022 Jun; 63(6):100215.
Application：WB-Ti, Mouse, Mouse lung.
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The effect of retinol binding protein on the proteome of C2C12 muscle cells.
Young PA, Leonard S, Martin DS, Findlay JB.
Diabetes/Metabolism Research and Reviews 2016 May; 32(4):379.
Application：WB, Mouse, C2C12 cells.
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Production of Functional Human Vitamin A Transporter/RBP Receptor (STRA6) for Structure Determination.
Breen CJ, Martin DS, Ma H, McQuaid K.
PLoS One 2015 Mar; 10(3):e122293.
Application：WB, Yeast , Broken yeast cells .
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Retinol-Binding Protein 4 and Its Membrane Receptor STRA6 Control Adipogenesis by Regulating Cellular Retinoid Homeostasis and Retinoic Acid Receptor α Activity.
Muenzner M, Tuvia N, Deutschmann C, Witte N, Tolkachov A, Valai A, Henze A, Sander LE, Raila J, Schupp M.
Molecular and Cellular Biology 2013 Oct; 33(20):4068.
Application：WB, Mouse, 3T3-L1 cells.
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Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A.
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