SEMA4A (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SEMA4A partial ORF ( NP_071762, 33 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GGGQGPMPRVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SEMA4A
Entrez GeneID
64218GeneBank Accession#
NM_022367Protein Accession#
NP_071762Gene Name
SEMA4A
Gene Alias
CORD10, FLJ12287, RP35, SEMAB, SEMB
Gene Description
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
Gene Ontology
HyperlinkGene Summary
SEMA4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in guidance of axonal migration during neuronal development and in immune responses.[supplied by OMIM
Other Designations
OTTHUMP00000015916|OTTHUMP00000015917|OTTHUMP00000015918|sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4A|semaphorin B
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Interactome
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Pathway
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Disease
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Publication Reference
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Sema4A responds to hypoxia and is involved in breast cancer progression.
Liu X, Sun Y, Tian W, Wang F, Lv X, Wang M, Sun T, Zhang J, Wang L, Han M.
Biological & Pharmaceutical Bulletin 2018 Sep; [Epub].
Application:Func, Human, MCF-7, MDA-MB-231 cells.
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Sema4A responds to hypoxia and is involved in breast cancer progression.
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