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LEPRE1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00064175-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human LEPRE1 protein.
  • Immunogen:
  • LEPRE1 (AAH15309, 1 a.a. ~ 390 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • 7.
  • PPIB Mutations Cause Severe Osteogenesis Imperfecta.
    van Dijk FS, Nesbitt IM, Zwikstra EH, Nikkels PG, Piersma SR, Fratantoni SA, Jimenez CR, Huizer M, Morsman AC, Cobben JM, van Roij MH, Elting MW, Verbeke JI, Wijnaendts LC, Shaw NJ, Hogler W, McKeown C, Sistermans EA, Dalton A, Meijers-Heijboer H, Pals G.Am J Hum Genet. 2009 Oct;85(4):521-7. Epub 2009 Sep 24.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • LEPRE1 MaxPab polyclonal antibody. Western Blot analysis of LEPRE1 expression in human placenta.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of LEPRE1 expression in transfected 293T cell line (H00064175-T01) by LEPRE1 MaxPab polyclonal antibody.

    Lane 1: LEPRE1 transfected lysate(42.9 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • LEPRE1
  • Gene Alias:
  • GROS1,MGC117314,P3H1
  • Gene Description:
  • leucine proline-enriched proteoglycan (leprecan) 1
  • Gene Summary:
  • This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Two alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000008736,growth suppressor 1,leprecan,leprecan 1,prolyl 3-hydroxylase 1
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