ERAP2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ERAP2 full-length ORF ( AAH17927.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSKYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLGMFKFHIIVFIFAHKTCFDLFPLSLSM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.5
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ERAP2
Entrez GeneID
64167GeneBank Accession#
BC017927.2Protein Accession#
AAH17927.1Gene Name
ERAP2
Gene Alias
FLJ23633, FLJ23701, FLJ23807, L-RAP, LRAP
Gene Description
endoplasmic reticulum aminopeptidase 2
Omim ID
609497Gene Ontology
HyperlinkGene Summary
Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).[supplied by OMIM
Other Designations
leukocyte-derived arginine aminopeptidase
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Interactome
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Disease
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