CRLF2 monoclonal antibody (M03), clone 4A11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CRLF2.
Immunogen
CRLF2 (NP_071431, 23 a.a. ~ 132 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QGGAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQD
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CRLF2 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — CRLF2
Entrez GeneID
64109GeneBank Accession#
NM_022148Protein Accession#
NP_071431Gene Name
CRLF2
Gene Alias
CRL2, CRLF2Y, TSLPR
Gene Description
cytokine receptor-like factor 2
Gene Ontology
HyperlinkGene Summary
Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the type I cytokine receptor family. Type I cytokine receptors share conserved structural features in their extracellular domain. Receptor complexes are typically heterodimeric, consisting of alpha chains, which provide ligand specificity, and beta (or gamma) chains, which are required for the formation of high-affinity binding sites and signal transduction.[supplied by OMIM
Other Designations
cytokine receptor CRL2 precusor|thymic stromal lymphopoietin receptor|thymic stromal-derived lymphopoietin receptor
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Interactome
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Pathway
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Disease
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