MCCC2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MCCC2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MCCC2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MCCC2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MCCC2
Entrez GeneID
64087GeneBank Accession#
MCCC2Gene Name
MCCC2
Gene Alias
MCCB
Gene Description
methylcrotonoyl-Coenzyme A carboxylase 2 (beta)
Gene Ontology
HyperlinkGene Summary
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq
Other Designations
biotin carboxylase|non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase
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