ELAC2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
ELAC2 transfected lysate.
Western Blot
Lane 1: ELAC2 transfected lysate ( 90.97 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ELAC2 full-length
Host
Human
Theoretical MW (kDa)
90.97
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ELAC2 antibody (H00060528-B01) by Western Blots.
SDS-PAGE Gel
ELAC2 transfected lysate.
Western Blot
Lane 1: ELAC2 transfected lysate ( 90.97 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ELAC2
Entrez GeneID
60528GeneBank Accession#
NM_018127.4Protein Accession#
NP_060597.3Gene Name
ELAC2
Gene Alias
ELC2, FLJ10530, FLJ36693, FLJ42848, HPC2
Gene Description
elaC homolog 2 (E. coli)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
elaC homolog 2|hereditary prostate cancer|putative prostate cancer susceptibility protein|tRNA Z (long form)
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Interactome
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Disease
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