ELAC2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of ELAC2 transfected lysate using rabbit polyclonal anti-ELAC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ELAC2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of ELAC2 transfected lysate using rabbit polyclonal anti-ELAC2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ELAC2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-ELAC2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-ELAC2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — ELAC2
Entrez GeneID
60528Gene Name
ELAC2
Gene Alias
ELC2, FLJ10530, FLJ36693, FLJ42848, HPC2
Gene Description
elaC homolog 2 (E. coli)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
elaC homolog 2|hereditary prostate cancer|putative prostate cancer susceptibility protein|tRNA Z (long form)
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Interactome
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Disease
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