ELAC2 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Western Blot (Tissue lysate)
ELAC2 MaxPab rabbit polyclonal antibody. Western Blot analysis of ELAC2 expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of ELAC2 expression in transfected 293T cell line (H00060528-T02) by ELAC2 MaxPab polyclonal antibody.
Lane 1: ELAC2 transfected lysate(92.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ELAC2 transfected lysate using anti-ELAC2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ELAC2 purified MaxPab mouse polyclonal antibody (B01P) (H00060528-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ELAC2 protein.
Immunogen
ELAC2 (NP_060597.3, 1 a.a. ~ 826 a.a) full-length human protein.
Sequence
MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSELNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (81); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ELAC2 MaxPab rabbit polyclonal antibody. Western Blot analysis of ELAC2 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of ELAC2 expression in transfected 293T cell line (H00060528-T02) by ELAC2 MaxPab polyclonal antibody.
Lane 1: ELAC2 transfected lysate(92.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ELAC2 transfected lysate using anti-ELAC2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ELAC2 purified MaxPab mouse polyclonal antibody (B01P) (H00060528-B01P). -
Gene Info — ELAC2
Entrez GeneID
60528GeneBank Accession#
NM_018127.4Protein Accession#
NP_060597.3Gene Name
ELAC2
Gene Alias
ELC2, FLJ10530, FLJ36693, FLJ42848, HPC2
Gene Description
elaC homolog 2 (E. coli)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
elaC homolog 2|hereditary prostate cancer|putative prostate cancer susceptibility protein|tRNA Z (long form)
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Interactome
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Disease
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