EDA2R DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human EDA2R DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — EDA2R
Entrez GeneID
60401GeneBank Accession#
NM_021783.2Protein Accession#
NP_068555.1Gene Name
EDA2R
Gene Alias
EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Gene Description
ectodysplasin A2 receptor
Omim ID
300276Gene Ontology
HyperlinkGene Summary
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq
Other Designations
EDA-A2 receptor|OTTHUMP00000023448|X-linked ectodysplasin receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member XEDAR
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Interactome
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Pathway
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Disease
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