EDA2R monoclonal antibody (M02), clone 3C1
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More Files
- More Functions
Western Blot (Cell lysate)
EDA2R monoclonal antibody (M02), clone 3C1. Western Blot analysis of EDA2R expression in Raw 264.7.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EDA2R is approximately 1ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.84 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant EDA2R.
Immunogen
EDA2R (NP_068555, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQ
Host
Mouse
Reactivity
Human, Mouse
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
EDA2R monoclonal antibody (M02), clone 3C1. Western Blot analysis of EDA2R expression in Raw 264.7.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EDA2R is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — EDA2R
Entrez GeneID
60401GeneBank Accession#
NM_021783Protein Accession#
NP_068555Gene Name
EDA2R
Gene Alias
EDA-A2R, EDAA2R, TNFRSF27, XEDAR
Gene Description
ectodysplasin A2 receptor
Omim ID
300276Gene Ontology
HyperlinkGene Summary
EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq
Other Designations
EDA-A2 receptor|OTTHUMP00000023448|X-linked ectodysplasin receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member XEDAR
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Interactome
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Pathway
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Disease
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