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Last updated: 2017/11/19

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EDA2R rabbit monoclonal antibody

  • Catalog # : H00060401-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human EDA2R peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human EDA2R is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human EDA2R peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • EDA2R
  • Gene Name:
  • EDA2R
  • Gene Alias:
  • EDA-A2R,EDAA2R,TNFRSF27,XEDAR
  • Gene Description:
  • ectodysplasin A2 receptor
  • Gene Summary:
  • EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq
  • Other Designations:
  • EDA-A2 receptor,OTTHUMP00000023448,X-linked ectodysplasin receptor,X-linked ectodysplasin-A2 receptor,tumor necrosis factor receptor superfamily member XEDAR
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