TRPV4 monoclonal antibody (M01), clone 4E11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TRPV4.
Immunogen
TRPV4 (NP_067638.3, 772 a.a. ~ 871 a.a) partial recombinant protein with GST-pstS1 tag.
Sequence
PDRRWCFRVDEVNWSHWNQNLGIINEDPGKNETYQYYGFSHTVGRLRRDRWSSVVPRVVELNKNSNPDEVVVPLDSMGNPRCDGHQQGYPRKWRTDDAPL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TRPV4 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — TRPV4
Entrez GeneID
59341GeneBank Accession#
NM_021625.4Protein Accession#
NP_067638.3Gene Name
TRPV4
Gene Alias
OTRPC4, TRP12, VR-OAC, VRL-2, VRL2, VROAC
Gene Description
transient receptor potential cation channel, subfamily V, member 4
Omim ID
605427Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OSM9-like transient receptor potential channel 4|osmosensitive transient receptor potential channel 4|transient receptor potential channel 12|vanilloid receptor-related osmotically activated channel
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Interactome
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Disease
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