ACE2 (Human) Recombinant Protein

Catalog # H00059272-H02

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Size:25 ug
Price: USD $ 721.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
SDS-PAGE Gel
QC Test

SDS-PAGE Gel

Western Blot
QC Test

Western Blot

  • Specification

    Product Description

    Purified ACE2 (NP_068576.1 , 18 a.a. - 740 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.

    Transfected Cell Line

    Human HEK293F cells

    Sequence

    QSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAYEWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRINDAFRLNDNSLEFLGIQPTLGPPNQPPVS

    Host

    Human

    Theoretical MW (kDa)

    82.61

    Form

    Liquid

    Preparation Method

    Transfection of pSuper-ACE2 plasmid into HEK293F cell, and the expressed protein was purified by Strep-Tactin affinity column.

    Purification

    Strep-Tactin affinity columns

    Concentration

    >= 10 ug/ml

    Quality Control Testing

    SDS-PAGE and Western Blot

    SDS-PAGE Gel

    Western Blot

    Storage Buffer

    100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot

    Enzyme-linked Immunoabsorbent Assay

    SDS-PAGE

  • Gene Info — ACE2

    Entrez GeneID

    59272

    GeneBank Accession#

    NM_021804.1

    Protein Accession#

    NP_068576.1

    Gene Name

    ACE2

    Gene Alias

    ACEH, DKFZp434A014

    Gene Description

    angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

    Omim ID

    300335

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq

    Other Designations

    ACE-related carboxypeptidase|OTTHUMP00000022963|angiotensin I converting enzyme 2|angiotensin converting enzyme-like protein

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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