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Last updated: 2016/12/4

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DNASE2B Pre-design Chimera RNAi

  • Catalog # : H00058511-R01
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  • Specification
  • Product Description:
  • Homo sapiens deoxyribonuclease II beta (DNASE2B), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_021233
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • DNASE2B
  • Gene Alias:
  • DLAD
  • Gene Description:
  • deoxyribonuclease II beta
  • Gene Summary:
  • The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • DNase II-like acid DNase,OTTHUMP00000011481,endonuclease DLAD,lysosomal DNase II
  • Gene Pathway
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