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Last updated: 2017/10/15

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CARD12 Pre-design Chimera RNAi

  • Catalog # : H00058484-R01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens caspase recruitment domain family, member 12 (CARD12), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_021209
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • NLRC4
  • Gene Alias:
  • CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,IPAF
  • Gene Description:
  • NLR family, CARD domain containing 4
  • Gene Summary:
  • In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM
  • Other Designations:
  • ICE-protease activating factor,NOD-like receptor C4,caspase recruitment domain family, member 12,caspase recruitment domain protein 12,nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
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