NGB monoclonal antibody (M01), clone 2B5-A7
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full length recombinant NGB.
Immunogen
NGB (AAH32509, 1 a.a. ~ 151 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MERPEPELIRQSWRAVSRSPLGHGTVLFARLFALEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLASLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWDGE
Host
Mouse
Reactivity
Human
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.35 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NGB is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — NGB
Entrez GeneID
58157GeneBank Accession#
BC032509Protein Accession#
AAH32509Gene Name
NGB
Gene Alias
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Gene Description
neuroglobin
Omim ID
605304Gene Ontology
HyperlinkGene Summary
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq
Other Designations
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Interactomes
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Diseases
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Publication Reference
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Polydatin protects neuronal cells from hydrogen peroxide damage by activating CREB/Ngb signaling.
Huihui Zhang, Yadan Li, Yu Xun, Hui Liu, Chenxi Wei, Hao Wang, Xiaoping Yang, Shishan Yuan, Ning Liu, Shuanglin Xiang.
Molecular MedicineRreports 2022 Jan; 25(1):9.
Application:WB-Ce, WB-Tr, Mouse, N2a cells.
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Polydatin protects neuronal cells from hydrogen peroxide damage by activating CREB/Ngb signaling.
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