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Last updated: 2016/12/4

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HAMP Pre-design Chimera RNAi

  • Catalog # : H00057817-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens hepcidin antimicrobial peptide (HAMP), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_021175
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • HAMP
  • Gene Alias:
  • HEPC,HEPCIDIN,HFE2B,LEAP-1,LEAP1,PLTR
  • Gene Description:
  • hepcidin antimicrobial peptide
  • Gene Summary:
  • The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
  • Other Designations:
  • liver-expressed antimicrobial peptide,putative liver tumor regressor
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