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Last updated: 2016/12/4

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HAMP (Human) Recombinant Protein (P01)

  • Catalog # : H00057817-P01
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  • Specification
  • Product Description:
  • Human HAMP full-length ORF ( AAH20612, 25 a.a. - 84 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • SVFPQQTGQLAELQPQDRAGARASWMPMFQRRRRRDTHFPICIFCCGCCHRSKCGMCCKT
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 32.34
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00057817-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Gene Name:
  • HAMP
  • Gene Alias:
  • HEPC,HEPCIDIN,HFE2B,LEAP-1,LEAP1,PLTR
  • Gene Description:
  • hepcidin antimicrobial peptide
  • Gene Summary:
  • The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
  • Other Designations:
  • liver-expressed antimicrobial peptide,putative liver tumor regressor
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