TRIB3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TRIB3 full-length ORF ( AAH27484, 1 a.a. - 358 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYRALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
65.12
Interspecies Antigen Sequence
Mouse (73); Rat (73)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TRIB3
Entrez GeneID
57761GeneBank Accession#
BC027484Protein Accession#
AAH27484Gene Name
TRIB3
Gene Alias
C20orf97, NIPK, SINK, SKIP3, TRB3
Gene Description
tribbles homolog 3 (Drosophila)
Omim ID
607898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq
Other Designations
neuronal cell death inducible putative kinase|p65-interacting inhibitor of NF-kappaB|tribbles 3
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Interactome
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Disease
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