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TRIB3 rabbit monoclonal antibody

  • Catalog # : H00057761-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TRIB3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TRIB3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TRIB3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • TRIB3
  • Gene Name:
  • TRIB3
  • Gene Alias:
  • C20orf97,NIPK,SINK,SKIP3,TRB3
  • Gene Description:
  • tribbles homolog 3 (Drosophila)
  • Gene Summary:
  • The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq
  • Other Designations:
  • neuronal cell death inducible putative kinase,p65-interacting inhibitor of NF-kappaB,tribbles 3
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