TRIB3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TRIB3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TRIB3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TRIB3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TRIB3
Entrez GeneID
57761GeneBank Accession#
TRIB3Gene Name
TRIB3
Gene Alias
C20orf97, NIPK, SINK, SKIP3, TRB3
Gene Description
tribbles homolog 3 (Drosophila)
Omim ID
607898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq
Other Designations
neuronal cell death inducible putative kinase|p65-interacting inhibitor of NF-kappaB|tribbles 3
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Interactome
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Disease
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