GPAM polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant GPAM.
Immunogen
GPAM (NP_065969, 749 a.a. ~ 828 a.a) partial recombinant protein with GST tag.
Sequence
PEYLQKLHKYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEYILSFVVL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.91 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — GPAM
Entrez GeneID
57678GeneBank Accession#
NM_020918Protein Accession#
NP_065969Gene Name
GPAM
Gene Alias
GPAT1, KIAA1560, MGC26846, RP11-426E5.2
Gene Description
glycerol-3-phosphate acyltransferase, mitochondrial
Omim ID
602395Gene Ontology
HyperlinkGene Summary
Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynthesis, is predicted to play a pivotal role in the regulation of cellular triacylglycerol and phospholipid levels. Two mammalian forms of GPAT have been identified on the basis of localization to either the endoplasmic reticulum or mitochondria.[supplied by OMIM
Other Designations
glycerol 3-phosphate acyltransferase, mitochondrial|mitochondrial glycerol 3-phosphate acyltransferase
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Interactome
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Pathway
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Disease
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Publication Reference
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Bezafibrate at clinically-relevant doses decreases serum/liver triglycerides via down-regulation of SREBP-1c in mice: a novel PPAR{alpha}-independent mechanism.
Nakajima T, Tanaka N, Kanbe H, Hara A, Kamijo Y, Zhang X, Gonzalez FJ, Aoyama T.
Molecular Pharmacology 2009 Apr; 75(4):782.
Application:WB, Mouse, Liver.
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Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+/-):LDLR (+/-) mice, an obese mouse model.
Li Y, Sugiyama E, Yokoyama S, Jiang L, Tanaka N, Aoyama T.
Lipids 2008 Mar; 43(4):301.
Application:WB, Mouse, Mouse liver.
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Bezafibrate at clinically-relevant doses decreases serum/liver triglycerides via down-regulation of SREBP-1c in mice: a novel PPAR{alpha}-independent mechanism.
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