RPTOR MaxPab rabbit polyclonal antibody (D01)
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More Files
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Immunoprecipitation
Immunoprecipitation of RPTOR transfected lysate using anti-RPTOR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RPTOR purified MaxPab mouse polyclonal antibody (B01P) (H00057521-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RPTOR protein.
Immunogen
RPTOR (AAH64515.1, 1 a.a. ~ 379 a.a) full-length human protein.
Sequence
MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNCIQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPGRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPPTYMHAMW
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of RPTOR transfected lysate using anti-RPTOR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RPTOR purified MaxPab mouse polyclonal antibody (B01P) (H00057521-B01P). -
Gene Info — RPTOR
Entrez GeneID
57521GeneBank Accession#
BC064515Protein Accession#
AAH64515.1Gene Name
RPTOR
Gene Alias
KOG1, Mip1
Gene Description
regulatory associated protein of MTOR, complex 1
Omim ID
607130Gene Ontology
HyperlinkGene Summary
This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats|regulatory associated protein of mTOR
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Interactome
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Pathway
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Disease
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