ISY1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ISY1 full-length ORF ( NP_065752.1, 1 a.a. - 285 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MARNAEKAMTALARFRQAQLEEGKVKERRPFLASECTELPKAEKWRRQIIGEISKKVAQIQNAGLGEFRIRDLNDEINKLLREKGHWEVRIKELGGPDYGKVGPKMLDHEGKEVPGNRGYKYFGAAKDLPGVRELFEKEPLPPPRKTRAELMKAIDFEYYGYLDEDDGVIVPLEQEYEKKLRAELVEKWKAEREARLARGEKEEEEEEEEEINIYAVTEEESDEEGSQEKGGDDSQQKFIAHVPVPSQQEIEEALVRRKKMELLQKYASETLQAQSEEARRLLGY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
59.4
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ISY1
Entrez GeneID
57461GeneBank Accession#
NM_020701.1Protein Accession#
NP_065752.1Gene Name
ISY1
Gene Alias
KIAA1160, fSAP33
Gene Description
ISY1 splicing factor homolog (S. cerevisiae)
Gene Ontology
HyperlinkOther Designations
ISY1 splicing factor homolog|OTTHUMP00000174311|functional spliceosome-associated protein 33
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Interactome
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Publication Reference
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The splicing component ISY1 regulates APE1 in base excision repair.
Aruna S Jaiswal, Elizabeth A Williamson, Gayathri Srinivasan, Kimi Kong, Carrie L Lomelino, Robert McKenna, Christi Walter, Patrick Sung, Satya Narayan, Robert Hromas.
DNA Repair 2020 Feb; 86:102769.
Application:Enzyme, Func, Recombinant proteins.
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The splicing component ISY1 regulates APE1 in base excision repair.
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