CLK4 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CLK4 full-length
Host
Human
Theoretical MW (kDa)
53.02
Interspecies Antigen Sequence
Mouse (97)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CLK4 antibody (H00057396-B01) by Western Blots.
SDS-PAGE Gel
CLK4 transfected lysate.
Western Blot
Lane 1: CLK4 transfected lysate ( 53.02 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CLK4
Entrez GeneID
57396GeneBank Accession#
NM_020666.2Protein Accession#
NP_065717.1Gene Name
CLK4
Gene Alias
DKFZp686A20267
Gene Description
CDC-like kinase 4
Omim ID
607969Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq
Other Designations
dual specificity protein kinase CLK4|protein serine threonine kinase Clk4
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