CORO1B monoclonal antibody (M01), clone 1E7
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CORO1B.
Immunogen
CORO1B (AAH06449, 1 a.a. ~ 489 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (92)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (79.53 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CORO1B monoclonal antibody (M01), clone 1E7 Western Blot analysis of CORO1B expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to CORO1B on formalin-fixed paraffin-embedded human lymphoma tissue. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CORO1B is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — CORO1B
Entrez GeneID
57175GeneBank Accession#
BC006449Protein Accession#
AAH06449Gene Name
CORO1B
Gene Alias
CORONIN-2, DKFZp762I166
Gene Description
coronin, actin binding protein, 1B
Omim ID
609849Gene Ontology
HyperlinkGene Summary
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).[supplied by OMIM
Other Designations
coronin, actin-binding protein, 1B
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Interactome
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Publication Reference
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Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells.
Samarin SN, Koch S, Ivanov AI, Parkos CA, Nusrat A.
Biochemical and Biophysical Research Communications 2009 Nov; 391(1):394.
Application:WB-Tr, Human, SK-CO15 cells.
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Coronin 1C negatively regulates cell-matrix adhesion and motility of intestinal epithelial cells.
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